Predicting DNA-Binding Specificities of Eukaryotic Transcription Factors
نویسندگان
چکیده
منابع مشابه
Predicting DNA-Binding Specificities of Eukaryotic Transcription Factors
Today, annotated amino acid sequences of more and more transcription factors (TFs) are readily available. Quantitative information about their DNA-binding specificities, however, are hard to obtain. Position frequency matrices (PFMs), the most widely used models to represent binding specificities, are experimentally characterized only for a small fraction of all TFs. Even for some of the most i...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2010
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0013876